Cinnamon in Nonalcoholic Fatty Liver Disease

Cinnamon (dalchini) helps improve lipid profiles and improve nonalcoholic fatty liver disease (NAFLD), according to a new Iranian trial reports Medscape. The report found that 12 weeks consumption of 1.5 grams cinnamon per day plus a balanced diet improves insulin resistance and NAFLD characteristics. The study by Dr. Azita Hekmatdoost is published online December 9 in the journal Nutrition Research.

Cinnamon has anti–oxidant and insulin–sensitizer properties.

In the study, 50 patients were randomized to two 750 mg capsules of cinnamon or placebo daily for 12 weeks. All patients were given advice on a balanced diet and physical activity. In both groups, LDL cholesterol dropped significantly but there was no significant change in serum HDL cholesterol levels. After 12 weeks, LDL levels were 55.8 mg/dL in the treatment group and 90.3 mg/dL in the placebo group (p=0.032).

In the active treatment group there were also significant decreases in the HOMA (Homeostatic Model Assessment) index, fasting blood glucose, total cholesterol, triglyceride, SGOT and SGPT levels. This was also true of gamma GT and hs–CRP.

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